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Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression

Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ(1) receptor (σ(1)R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ(1)R stimulation reportedly ameliorates depression-like...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shinoda, Yasuharu, Tagashira, Hideaki, Bhuiyan, Md. Shenuarin, Hasegawa, Hideyuki, Kanai, Hiroshi, Zhang, Chen, Han, Feng, Fukunaga, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065174/
https://ncbi.nlm.nih.gov/pubmed/27741227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163992
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