Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression

Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ(1) receptor (σ(1)R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ(1)R stimulation reportedly ameliorates depression-like...

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Vydáno v:PLoS One
Hlavní autoři: Shinoda, Yasuharu, Tagashira, Hideaki, Bhuiyan, Md. Shenuarin, Hasegawa, Hideyuki, Kanai, Hiroshi, Zhang, Chen, Han, Feng, Fukunaga, Kohji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065174/
https://ncbi.nlm.nih.gov/pubmed/27741227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163992
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