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Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function
Zfp423 encodes a 30-zinc finger transcription factor that intersects several canonical signaling pathways. Zfp423 mutations result in ciliopathy-related phenotypes, including agenesis of the cerebellar vermis in mice and Joubert syndrome (JBTS19) and nephronophthisis (NPHP14) in humans. Unlike most...
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| Gepubliceerd in: | PLoS Genet |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065120/ https://ncbi.nlm.nih.gov/pubmed/27727273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006357 |
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