Chronic exposure to trichloroethylene increases DNA methylation of the Ifng promoter in CD4(+) T cells

CD4(+) T cells in female MRL+/+ mice exposed to solvent and water pollutant trichloroethylene (TCE) skew toward effector/memory CD4(+) T cells, and demonstrate seemingly non-monotonic alterations in IFN-γ production. In the current study we examined the mechanism for this immunotoxicity using effect...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Toxicol Lett
Main Authors: Gilbert, Kathleen M., Blossom, Sarah J., Erickson, Stephen W., Broadfoot, Brannon, West, Kirk, Bai, Shasha, Li, Jingyun, Cooney, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065104/
https://ncbi.nlm.nih.gov/pubmed/27553676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2016.08.017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados