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Epigenetic Alterations May Regulate Temporary Reversal of CD4(+) T Cell Activation Caused by Trichloroethylene Exposure
Previous studies have shown that short-term (4 weeks) or chronic (32 weeks) exposure to trichloroethylene (TCE) in drinking water of female MRL+/+ mice generated CD4(+) T cells that secreted increased levels of interferon (IFN)-γ and expressed an activated (CD44(hi)CD62L(lo)) phenotype. In contrast,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327872/ https://ncbi.nlm.nih.gov/pubmed/22407948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs093 |
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