Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

The antipsychotic clozapine is uniquely effective in the management of schizophrenia; however, its use is limited by its potential to induce agranulocytosis. The causes of this, and of its precursor neutropenia, are largely unknown, although genetic factors have an important role. We sought risk all...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Psychiatry
Autores principales: Legge, S E, Hamshere, M L, Ripke, S, Pardinas, A F, Goldstein, J I, Rees, E, Richards, A L, Leonenko, G, Jorskog, L F, Chambert, K D, Collier, D A, Genovese, G, Giegling, I, Holmans, P, Jonasdottir, A, Kirov, G, McCarroll, S A, MacCabe, J H, Mantripragada, K, Moran, J L, Neale, B M, Stefansson, H, Rujescu, D, Daly, M J, Sullivan, P F, Owen, M J, O'Donovan, M C, Walters, J T R
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065090/
https://ncbi.nlm.nih.gov/pubmed/27400856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.97
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares