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Mechanical properties of the tumor stromal microenvironment probed in vitro and ex vivo by in situ-calibrated optical trap-based active microrheology

One of the hallmarks of the malignant transformation of epithelial tissue is the modulation of stromal components of the microenvironment. In particular, aberrant extracellular matrix (ECM) remodeling and stiffening enhances tumor growth and survival and promotes metastasis. Type I collagen is one o...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Staunton, Jack R, Vieira, Wilfred, Fung, King Leung, Lake, Ross, Devine, Alexus, Tanner, Kandice
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065074/
https://ncbi.nlm.nih.gov/pubmed/27752289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-016-0460-9
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