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The cystine/glutamate antiporter system x(c)(−) drives breast tumor cell glutamate release and cancer-induced bone pain

Bone is one of the leading sites of metastasis for frequently diagnosed malignancies, including those arising in the breast, prostate and lung. Although these cancers develop unnoticed and are painless in their primary sites, bone metastases result in debilitating pain. Deeper investigation of this...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Slosky, Lauren M., BassiriRad, Neemah M., Symons, Ashley M., Thompson, Michelle, Doyle, Timothy, Forte, Brittany L., Staatz, William D., Bui, Lynn, Neumann, William L., Mantyh, Patrick W., Salvemini, Daniela, Largent-Milnes, Tally M., Vanderah, Todd W.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065056/
https://ncbi.nlm.nih.gov/pubmed/27482630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000681
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