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Crystal structure and interaction studies of the human FBxo3 ApaG domain

Transcriptional activation of proinflammatory cytokines, mediated by tumor necrosis factor receptor-associated factors (TRAFs), is in part triggered by the degradation of the F-box protein, FBxl2, via an E3 ligase that contains another F-box protein, FBxo3. The ApaG domain of FBxo3 is required for t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Krzysiak, Troy C., Chen, Bill B., Lear, Travis, Mallampalli, Rama K., Gronenborn, Angela M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065005/
https://ncbi.nlm.nih.gov/pubmed/27010866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13721
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