Elimination of Chronic Lymphocytic Leukemia Cells in Stromal Microenvironment by Targeting CPT with an Anti-Angina Drug Perhexiline

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western countries and is currently incurable due in part to difficulty in eliminating the leukemia cells protected by stromal microenvironment. Based on previous observations that CLL cells exhibit mitochondrial dysfunction...

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Udgivet i:Oncogene
Main Authors: Liu, Pan-pan, Liu, Jinyun, Jiang, Wen-qi, Carew, Jennifer S., Ogasawara, Marcia A., Pelicano, Hélène, Croce, Carlo M., Estrov, Zeev, Xu, Rui-hua, Keating, Michael J., Huang, Peng
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064824/
https://ncbi.nlm.nih.gov/pubmed/27065330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.103
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