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In vivo dendritic cell targeting cellular vaccine induces CD4(+) Tfh cell-dependent antibody against influenza virus

An induction of long-term cellular and humoral immunity is for the goal of vaccines, but the combination of antigens and adjuvant remain unclear. Here, we show, using a cellular vaccine carrying foreign protein antigen plus iNKT cell glycolipid antigen, designated as artificial adjuvant vector cells...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamasaki, Satoru, Shimizu, Kanako, Kometani, Kohei, Sakurai, Maki, Kawamura, Masami, Fujii, Shin-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064395/
https://ncbi.nlm.nih.gov/pubmed/27739478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35173
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