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A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes

Insulin receptor substrates (IRSs) are major targets of insulin receptor tyrosine kinases. Here we identified diacylglycerol kinase zeta (DGKζ) as an IRS-1-associated protein, and examined roles of DGKζ in glucose transporter 4 (GLUT4) translocation to the plasma membrane. When DGKζ was knocked-down...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Liu, TingYu, Yu, BuChin, Kakino, Mamoru, Fujimoto, Hitoshi, Ando, Yasutoshi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064357/
https://ncbi.nlm.nih.gov/pubmed/27739494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35438
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