Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer deaths. Molecularly targeted therapies (e.g. bevacizumab) have improved survival rates but drug resistance ultimately develops and newer therapies are required. We identified quininib as a small molecule drug with anti-angiogenic activity using in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Murphy, Adrian G., Casey, Rory, Maguire, Aoife, Tosetto, Miriam, Butler, Clare T., Conroy, Emer, Reynolds, Alison L., Sheahan, Kieran, O’Donoghue, Diarmuid, Gallagher, William M., Fennelly, David, Kennedy, Breandán N., O’Sullivan, Jacintha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064353/
https://ncbi.nlm.nih.gov/pubmed/27739445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34523
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