1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

Colorectal cancer (CRC) is the second leading cause of cancer associated deaths in developed countries. Cancer progression and metastatic spread is reliant on new blood vasculature, or angiogenesis. Tumour-related angiogenesis is regulated by pro- and anti-angiogenic factors secreted from malignant...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Butler, Clare T., Kennedy, Susan A., Buckley, Amy, Doyle, Ronan, Conroy, Emer, Gallagher, William M., O’Sullivan, Jacintha, Kennedy, Breandán N.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557215/
https://ncbi.nlm.nih.gov/pubmed/31217905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26966
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