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1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

Colorectal cancer (CRC) is the second leading cause of cancer associated deaths in developed countries. Cancer progression and metastatic spread is reliant on new blood vasculature, or angiogenesis. Tumour-related angiogenesis is regulated by pro- and anti-angiogenic factors secreted from malignant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Butler, Clare T., Kennedy, Susan A., Buckley, Amy, Doyle, Ronan, Conroy, Emer, Gallagher, William M., O’Sullivan, Jacintha, Kennedy, Breandán N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557215/
https://ncbi.nlm.nih.gov/pubmed/31217905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26966
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