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A Facile, Improved Synthesis of Sildenafil and Its Analogues
This paper describes the facile synthesis of sildenafil citrate (1) and its related compounds through an improved chlorosulfonation reaction using chlorosulfonic acid and thionyl chloride. This synthesis results in pure sildenafil with high yield. The structures of the compounds were determined with...
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| Publicado no: | Sci Pharm |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064236/ https://ncbi.nlm.nih.gov/pubmed/28117311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/scipharm84030447 |
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