Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer

Oncogenic KRAS contributes to malignant transformation, antiapoptosis, and metastasis in multiple human cancers, such as lung, colon, and pancreatic cancers and melanoma. MicroRNAs (miRNAs) are endogenous 18- to 25-nucleotide noncoding small RNAs that regulate gene expression in a sequence-specific...

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Pubblicato in:Mol Cell Biol
Autori principali: Zhong, Xiaomin, Zheng, Lan, Shen, Jianfeng, Zhang, Dongmei, Xiong, Minmin, Zhang, Youyou, He, Xinhong, Tanyi, Janos L., Yang, Feng, Montone, Kathleen T., Chen, Xiaojun, Xu, Congjian, Xiang, Andy P., Huang, Qihong, Xu, Xiaowei, Zhang, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064220/
https://ncbi.nlm.nih.gov/pubmed/27550813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-16
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