Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals

Macrophages play crucial roles in host defence and tissue homoeostasis, processes in which both environmental stimuli and intracellularly generated metabolites influence activation of macrophages. Activated macrophages are classified into M1 and M2 macrophages. It remains unclear how intracellular n...

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Published in:Nat Commun
Main Authors: Kimura, Tetsuya, Nada, Shigeyuki, Takegahara, Noriko, Okuno, Tatsusada, Nojima, Satoshi, Kang, Sujin, Ito, Daisuke, Morimoto, Keiko, Hosokawa, Takashi, Hayama, Yoshitomo, Mitsui, Yuichi, Sakurai, Natsuki, Sarashina-Kida, Hana, Nishide, Masayuki, Maeda, Yohei, Takamatsu, Hyota, Okuzaki, Daisuke, Yamada, Masaki, Okada, Masato, Kumanogoh, Atsushi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064021/
https://ncbi.nlm.nih.gov/pubmed/27731330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13130
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