mTOR Complex Signaling through the SEMA4A–Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8(+) T Cells

Mammalian target of rapamycin (mTOR) plays crucial roles in activation and differentiation of diverse types of immune cells. Although several lines of evidence have demonstrated the importance of mTOR-mediated signals in CD4(+) T cell responses, the involvement of mTOR in CD8(+) T cell responses is...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Ito, Daisuke, Nojima, Satoshi, Nishide, Masayuki, Okuno, Tatsusada, Takamatsu, Hyota, Kang, Sujin, Kimura, Tetsuya, Yoshida, Yuji, Morimoto, Keiko, Maeda, Yohei, Hosokawa, Takashi, Toyofuku, Toshihiko, Ohshima, Jun, Kamimura, Daisuke, Yamamoto, Masahiro, Murakami, Masaaki, Morii, Eiichi, Rakugi, Hiromi, Isaka, Yoshitaka, Kumanogoh, Atsushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2015
Soggetti:
Immune Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505953/
https://ncbi.nlm.nih.gov/pubmed/26116513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403038
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