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Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause or the consequence of the unique function of...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Vannini, Nicola, Girotra, Mukul, Naveiras, Olaia, Nikitin, Gennady, Campos, Vasco, Giger, Sonja, Roch, Aline, Auwerx, Johan, Lutolf, Matthias P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064016/
https://ncbi.nlm.nih.gov/pubmed/27731316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13125
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