Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma

The biochemical mechanisms through which eosinophils contribute to asthma pathogenesis are unclear. Here we show eosinophil peroxidase (EPO), an abundant granule protein released by activated eosinophils, contributes to characteristic asthma-related phenotypes through oxidative posttranslational mod...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Zeneng, DiDonato, Joseph A., Buffa, Jennifer, Comhair, Suzy A., Aronica, Mark A., Dweik, Raed A., Lee, Nancy A., Lee, James J., Thomassen, Mary Jane, Kavuru, Mani, Erzurum, Serpil C., Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063994/
https://ncbi.nlm.nih.gov/pubmed/27587397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750034
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