PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery

Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type 2 diabetes (T2D). The role of pancreatic islet function in this restoration of normoglycemia has not been fully elucidated. Using the diabetic Goto-Kakizaki (GK) rat model, we demonstrate that RYGB...

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Publicat a:Cell Rep
Autors principals: Ramracheya, Reshma D., McCulloch, Laura J., Clark, Anne, Wiggins, David, Johannessen, Helene, Olsen, Magnus Kringstad, Cai, Xing, Zhao, Chun-Mei, Chen, Duan, Rorsman, Patrik
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
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Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063952/
https://ncbi.nlm.nih.gov/pubmed/27117413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.091
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