Oral quercetin administration transiently protects respiratory function in dystrophin‐deficient mice

KEY POINT: PGC‐1α pathway activation has been shown to decrease disease severity and can be driven by quercetin. Oral quercetin supplementation protected respiratory function for 4–6 months during a 12 month dosing regimen. This transient protection was probably due to a failure to sustain elevated...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Physiol
Huvudupphovsmän: Selsby, Joshua T., Ballmann, Christopher G., Spaulding, Hannah R., Ross, Jason W., Quindry, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Muscle
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063947/
https://ncbi.nlm.nih.gov/pubmed/27094343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272057
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