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Nutraceutical and pharmaceutical cocktails did not improve muscle function or reduce histological damage in D2-mdx mice
Progressive muscle injury and weakness are hallmarks of Duchenne muscular dystrophy. We showed previously that quercetin (Q) partially protected dystrophic limb muscles from disease-related injury. As quercetin activates PGC-1α through Sirtuin-1, an NAD(+)-dependent deacetylase, the depleted NAD(+)...
Enregistré dans:
| Publié dans: | J Appl Physiol (1985) |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7276925/ https://ncbi.nlm.nih.gov/pubmed/31295065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00162.2019 |
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