Functional characterization of DNA methylation in the oligodendrocyte lineage

Oligodendrocytes derive from progenitors (OPC) through the interplay of epigenomic and transcriptional events. By integrating high-resolution methylomics, RNA-sequencing and multiple transgenic lines, this study defines the role of DNMT1 in developmental myelination. We detected hypermethylation of...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Moyon, Sarah, Huynh, Jimmy L., Dutta, Dipankar, Zhang, Fan, Ma, Dan, Yoo, Seungyeul, Lawrence, Rebecca, Wegner, Michael, John, Gareth R., Emery, Ben, Lubetzki, Catherine, Franklin, Robin J. M., Fan, Guoping, Zhu, Jun, Dupree, Jeffrey L., Casaccia, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063656/
https://ncbi.nlm.nih.gov/pubmed/27149841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.060
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