Functional characterization of DNA methylation in the oligodendrocyte lineage

Oligodendrocytes derive from progenitors (OPC) through the interplay of epigenomic and transcriptional events. By integrating high-resolution methylomics, RNA-sequencing and multiple transgenic lines, this study defines the role of DNMT1 in developmental myelination. We detected hypermethylation of...

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Publicado en:Cell Rep
Autores principales: Moyon, Sarah, Huynh, Jimmy L., Dutta, Dipankar, Zhang, Fan, Ma, Dan, Yoo, Seungyeul, Lawrence, Rebecca, Wegner, Michael, John, Gareth R., Emery, Ben, Lubetzki, Catherine, Franklin, Robin J. M., Fan, Guoping, Zhu, Jun, Dupree, Jeffrey L., Casaccia, Patrizia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063656/
https://ncbi.nlm.nih.gov/pubmed/27149841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.060
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