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Actin filaments as dynamic reservoirs for Drp1 recruitment

Drp1 is a dynamin-family GTPase recruited to mitochondria and peroxisomes, where it oligomerizes and drives membrane fission. Regulation of mitochondrial Drp1 recruitment is not fully understood. We previously showed that Drp1 binds actin filaments directly, and actin polymerization is necessary for...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Hatch, Anna L., Ji, Wei-Ke, Merrill, Ronald A., Strack, Stefan, Higgs, Henry N.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063618/
https://ncbi.nlm.nih.gov/pubmed/27559132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0193
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