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Actin filaments as dynamic reservoirs for Drp1 recruitment

Drp1 is a dynamin-family GTPase recruited to mitochondria and peroxisomes, where it oligomerizes and drives membrane fission. Regulation of mitochondrial Drp1 recruitment is not fully understood. We previously showed that Drp1 binds actin filaments directly, and actin polymerization is necessary for...

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Pubblicato in:Mol Biol Cell
Autori principali: Hatch, Anna L., Ji, Wei-Ke, Merrill, Ronald A., Strack, Stefan, Higgs, Henry N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063618/
https://ncbi.nlm.nih.gov/pubmed/27559132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0193
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