Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems

A major hurdle for in vitro culturing of primary endothelial cells (ECs) is that they readily dedifferentiate, hampering their use for therapeutic applications. Human embryonic stem cells (hESCs) may provide an unlimited cell source; however, most current protocols deriving endothelial progenitor ce...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Nguyen, Mien T.X., Okina, Elena, Chai, Xiaoran, Tan, Kok Hian, Hovatta, Outi, Ghosh, Sujoy, Tryggvason, Karl
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063508/
https://ncbi.nlm.nih.gov/pubmed/27693424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.017
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