New developments in the management of non-small-cell lung cancer, focus on rociletinib: what went wrong?

Recently, the development of the third-generation epidermal growth factor receptor-small molecule inhibitor (EGFR-TKI) rociletinib had failed. In this review, the wide-ranging aspects of the evolution of EGFR-TKIs were collected, with a special focus on rociletinib. The influence of different oncoge...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Van Der Steen, Nele, Caparello, Chiara, Rolfo, Christian, Pauwels, Patrick, Peters, Godefridus J, Giovannetti, Elisa
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063481/
https://ncbi.nlm.nih.gov/pubmed/27785053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S97644
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