Expression and Functions of Immediate Early Response Gene X-1 (IEX-1) in Rheumatoid Arthritis Synovial Fibroblasts

In rheumatoid arthritis (RA), synovial fibroblasts (RA-SFs) accumulate in affected joints, where they play roles in inflammation and joint destruction. RA-SFs exhibit tumor-like proliferation and are resistant to apoptosis. Although RA-SF activation is well described, negative regulators of RA-SF ac...

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Veröffentlicht in:PLoS One
Hauptverfasser: Morinobu, Akio, Tanaka, Shino, Nishimura, Keisuke, Takahashi, Soshi, Kageyama, Goichi, Miura, Yasushi, Kurosaka, Masahiro, Saegusa, Jun, Kumagai, Shunichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063363/
https://ncbi.nlm.nih.gov/pubmed/27736946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164350
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