Tyrosine Kinase Inhibitors Regulate OPG through Inhibition of PDGFRβ

Nilotinib and imatinib are tyrosine kinase inhibitors (TKIs) used in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). In vitro, imatinib and nilotinib inhibit osteoclastogenesis, and in patients they reduce levels of bone resorption. One of the mechanisms t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: O’Sullivan, Susannah, Tay, Mei Lin, Lin, Jian-Ming, Bava, Usha, Callon, Karen, Cornish, Jillian, Naot, Dorit, Grey, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063333/
https://ncbi.nlm.nih.gov/pubmed/27737004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164727
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