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HtrA1 Proteolysis of ApoE in vitro is Allele Selective
Apolipoprotein E (ApoE) belongs to a large class of proteins that solubilize lipids for physiological transport. Humans have three different APOE alleles—APOE ε2, APOE ε3 and APOE ε4—and genetic studies identified ApoE4 as the strongest genetic risk factor for Alzheimer’s disease (AD). People who ar...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063305/ https://ncbi.nlm.nih.gov/pubmed/27379525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03463 |
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