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Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) ins...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hurtado-Roca, Yamilee, Ledesma, Marta, Gonzalez-Lazaro, Monica, Moreno-Loshuertos, Raquel, Fernandez-Silva, Patricio, Enriquez, Jose Antonio, Laclaustra, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063275/
https://ncbi.nlm.nih.gov/pubmed/27736919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163770
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