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Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) ins...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Hurtado-Roca, Yamilee, Ledesma, Marta, Gonzalez-Lazaro, Monica, Moreno-Loshuertos, Raquel, Fernandez-Silva, Patricio, Enriquez, Jose Antonio, Laclaustra, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063275/
https://ncbi.nlm.nih.gov/pubmed/27736919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163770
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