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The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition

The design of multitarget‐directed ligands is a promising strategy for discovering innovative drugs. Here, we report a mechanistic study that clarifies key aspects of the dual inhibition of the fatty acid amide hydrolase (FAAH) and the cyclooxygenase (COX) enzymes by a new multitarget‐directed ligan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ChemMedChem
Hauptverfasser: Palermo, Giulia, Favia, Angelo D., Convertino, Marino, De Vivo, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063142/
https://ncbi.nlm.nih.gov/pubmed/26593700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500507
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