Human CDK18 promotes replication stress signaling and genome stability

Cyclin-dependent kinases (CDKs) coordinate cell cycle checkpoints with DNA repair mechanisms that together maintain genome stability. However, the myriad mechanisms that can give rise to genome instability are still to be fully elucidated. Here, we identify CDK18 (PCTAIRE 3) as a novel regulator of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Barone, Giancarlo, Staples, Christopher J., Ganesh, Anil, Patterson, Karl W., Bryne, Dominic P., Myers, Katie N., Patil, Abhijit A., Eyers, Claire E., Maslen, Sarah, Skehel, J. Mark, Eyers, Patrick A., Collis, Spencer J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062979/
https://ncbi.nlm.nih.gov/pubmed/27382066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw615
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