Human CDK18 promotes replication stress signaling and genome stability

Cyclin-dependent kinases (CDKs) coordinate cell cycle checkpoints with DNA repair mechanisms that together maintain genome stability. However, the myriad mechanisms that can give rise to genome instability are still to be fully elucidated. Here, we identify CDK18 (PCTAIRE 3) as a novel regulator of...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Barone, Giancarlo, Staples, Christopher J., Ganesh, Anil, Patterson, Karl W., Bryne, Dominic P., Myers, Katie N., Patil, Abhijit A., Eyers, Claire E., Maslen, Sarah, Skehel, J. Mark, Eyers, Patrick A., Collis, Spencer J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062979/
https://ncbi.nlm.nih.gov/pubmed/27382066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw615
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