MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Through an RNAi-based screen for previously uncharacterized regulators of genome stability, we have identified the human protein C5orf45 as an important factor in preventing the accumulation of DNA damage in human cells. Here, we functionally characterize C5orf45 as a binding partner of the MRE11-RA...

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Publicat a:Cell Rep
Autors principals: Staples, Christopher J., Barone, Giancarlo, Myers, Katie N., Ganesh, Anil, Gibbs-Seymour, Ian, Patil, Abhijit A., Beveridge, Ryan D., Daye, Caroline, Beniston, Richard, Maslen, Sarah, Ahel, Ivan, Skehel, J. Mark, Collis, Spencer J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014761/
https://ncbi.nlm.nih.gov/pubmed/27568553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.087
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