MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Through an RNAi-based screen for previously uncharacterized regulators of genome stability, we have identified the human protein C5orf45 as an important factor in preventing the accumulation of DNA damage in human cells. Here, we functionally characterize C5orf45 as a binding partner of the MRE11-RA...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Staples, Christopher J., Barone, Giancarlo, Myers, Katie N., Ganesh, Anil, Gibbs-Seymour, Ian, Patil, Abhijit A., Beveridge, Ryan D., Daye, Caroline, Beniston, Richard, Maslen, Sarah, Ahel, Ivan, Skehel, J. Mark, Collis, Spencer J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014761/
https://ncbi.nlm.nih.gov/pubmed/27568553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.087
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