MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis

Myogenic regulatory factors of the MyoD family have the ability to reprogram differentiated cells toward a myogenic fate. In this study, we demonstrate that Six1 or Six4 are required for the reprogramming by MyoD of mouse embryonic fibroblasts (MEFs). Using microarray experiments, we found 761 genes...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Santolini, Marc, Sakakibara, Iori, Gauthier, Morgane, Ribas-Aulinas, Francesc, Takahashi, Hirotaka, Sawasaki, Tatsuya, Mouly, Vincent, Concordet, Jean-Paul, Defossez, Pierre-Antoine, Hakim, Vincent, Maire, Pascal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062961/
https://ncbi.nlm.nih.gov/pubmed/27302134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw512
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items