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Epigenetic polypharmacology: from combination therapy to multitargeted drugs

The modern drug discovery process has largely focused its attention in the so-called magic bullets, single chemical entities that exhibit high selectivity and potency for a particular target. This approach was based on the assumption that the deregulation of a protein was causally linked to a diseas...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: de Lera, Angel R., Ganesan, A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062873/
https://ncbi.nlm.nih.gov/pubmed/27752293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0271-9
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