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Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

Next generation drug screening could benefit greatly from in vivo studies, using small animal models such as Caenorhabditis elegans for hit identification and lead optimization. Current in vivo assays can operate either at low throughput with high resolution or with low resolution at high throughput...

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書目詳細資料
發表在:Nat Commun
Main Authors: Mondal, Sudip, Hegarty, Evan, Martin, Chris, Gökçe, Sertan Kutal, Ghorashian, Navid, Ben-Yakar, Adela
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062571/
https://ncbi.nlm.nih.gov/pubmed/27725672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13023
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