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Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

Next generation drug screening could benefit greatly from in vivo studies, using small animal models such as Caenorhabditis elegans for hit identification and lead optimization. Current in vivo assays can operate either at low throughput with high resolution or with low resolution at high throughput...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Mondal, Sudip, Hegarty, Evan, Martin, Chris, Gökçe, Sertan Kutal, Ghorashian, Navid, Ben-Yakar, Adela
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062571/
https://ncbi.nlm.nih.gov/pubmed/27725672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13023
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