Regioselective Synthesis of a Family of β‐Lactams Bearing a Triazole Moiety as Potential Apoptosis Inhibitors

Apoptosis is a biological process important to several human diseases; it is strongly regulated through protein–protein interactions and complex formation. We previously reported the synthesis of apoptosis inhibitors bearing an exocyclic triazole amide isoster by using an Ugi four‐component coupling...

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Bibliographic Details
Published in:ChemistryOpen
Main Authors: Garrido, Maria, Corredor, Miriam, Orzáez, Mar, Alfonso, Ignacio, Messeguer, Angel
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062015/
https://ncbi.nlm.nih.gov/pubmed/27777842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600052
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