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Synthesis of new Schiff bases bearing 1,2,4-triazole, thiazolidine and chloroazetidine moieties and their pharmacological evaluation

New compounds based on oxindole moiety were synthesized via the reaction of 5-substitued isatins 1a–e with different nucleophiles such as benzidine, 3,3′-dimethoxybenzidine 2a,b and 2,6-diaminopyridine 3 to afford three different classes of bis-Schiff bases 4a–e, 5a–e and 6a–e, respectively. The str...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Kandile, Nadia G., Mohamed, Mansoura I., Ismaeel, Hind M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009854/
https://ncbi.nlm.nih.gov/pubmed/27766903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1238365
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