Quantification of Cellular and Nuclear Uptake Rates of Polymeric Gene Delivery Nanoparticles and DNA Plasmids via Flow Cytometry

Non-viral, biomaterial-mediated gene delivery has the potential to treat many diseases, but is limited by low efficacy. Elucidating the bottlenecks of plasmid mass transfer can enable an improved understanding of biomaterial structure-function relationships, leading to next-generation rationally des...

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Библиографические подробности
Опубликовано в: :Acta Biomater
Главные авторы: Bishop, Corey J., Majewski, Rebecca L., Guiriba, Toni-Rose M., Wilson, David R., Bhise, Nupura S., Quiñones-Hinojosa, Alfredo, Green, Jordan J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061650/
https://ncbi.nlm.nih.gov/pubmed/27019146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.03.036
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