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Establishment of an Inducible HBV Stable Cell Line that Expresses cccDNA-dependent Epitope-tagged HBeAg for Screening of cccDNA Modulators

Hepatitis B virus (HBV) covalently closed circular (ccc) DNA is essential to the virus life cycle, its elimination during chronic infection is considered critical to a durable therapy but has not been achieved by current antivirals. Despite being essential, cccDNA has not been the major target of hi...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Cai, Dawei, Wang, Xiaohe, Yan, Ran, Mao, Richeng, Liu, Yuanjie, Ji, Changhua, Cuconati, Andrea, Guo, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5060949/
https://ncbi.nlm.nih.gov/pubmed/27185623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.05.005
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