Purification of human leukotriene C4 synthase.

Leukotriene (LT) C4 synthase, the enzyme that catalyzes the conjugation of LTA4 with reduced glutathione to form LTC4, was purified to homogeneity from the KG-1 myeloid cell line after solubilization of the microsomes utilizing a combination of 0.4% sodium deoxycholate and 0.4% Triton X-102. The sol...

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Bibliografiske detaljer
Main Authors: Penrose, J F, Gagnon, L, Goppelt-Struebe, M, Myers, P, Lam, B K, Jack, R M, Austen, K F, Soberman, R J
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50601/
https://ncbi.nlm.nih.gov/pubmed/1454853
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