Purification of human leukotriene C4 synthase.

Leukotriene (LT) C4 synthase, the enzyme that catalyzes the conjugation of LTA4 with reduced glutathione to form LTC4, was purified to homogeneity from the KG-1 myeloid cell line after solubilization of the microsomes utilizing a combination of 0.4% sodium deoxycholate and 0.4% Triton X-102. The sol...

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Detalhes bibliográficos
Main Authors: Penrose, J F, Gagnon, L, Goppelt-Struebe, M, Myers, P, Lam, B K, Jack, R M, Austen, K F, Soberman, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50601/
https://ncbi.nlm.nih.gov/pubmed/1454853
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