Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

DNA N(6)-methyldeoxyadenosine (6mA) is a well-known prokaryotic DNA modification that has been shown to exist and play epigenetic roles in eukaryotic DNA. Here we report that 6mA accumulates up to ∼0.1–0.2% of total deoxyadenosine during early embryogenesis of vertebrates, but diminishes to the back...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Jianzhao, Zhu, Yuanxiang, Luo, Guan-Zheng, Wang, Xinxia, Yue, Yanan, Wang, Xiaona, Zong, Xin, Chen, Kai, Yin, Hang, Fu, Ye, Han, Dali, Wang, Yizhen, Chen, Dahua, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059759/
https://ncbi.nlm.nih.gov/pubmed/27713410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13052
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