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Tetrameric structure of the restriction DNA glycosylase R.PabI in complex with nonspecific double-stranded DNA

R.PabI is a type II restriction enzyme that recognizes the 5′-GTAC-3′ sequence and belongs to the HALFPIPE superfamily. Although most restriction enzymes cleave phosphodiester bonds at specific sites by hydrolysis, R.PabI flips the guanine and adenine bases of the recognition sequence out of the DNA...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wang, Delong, Miyazono, Ken-ichi, Tanokura, Masaru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059719/
https://ncbi.nlm.nih.gov/pubmed/27731370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35197
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