The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams

The optimal recognition of penicillin determinants, including amoxicillin (AX), by specific IgE antibodies is widely believed to require covalent binding to a carrier molecule. The nature of the carrier and its contribution to the antigenic determinant is not well known. Here we aimed to evaluate th...

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Udgivet i:Sci Rep
Main Authors: Ariza, Adriana, Mayorga, Cristobalina, Salas, María, Doña, Inmaculada, Martín-Serrano, Ángela, Pérez-Inestrosa, Ezequiel, Pérez-Sala, Dolores, Guzmán, Antonio E., Montañez, María I., Torres, María J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059705/
https://ncbi.nlm.nih.gov/pubmed/27731424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35113
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