Characterization by yeast artificial chromosome cloning of the linked apolipoprotein(a) and plasminogen genes and identification of the apolipoprotein(a) 5' flanking region.

The apoprotein(a) [apo(a)] gene encodes a protein component of the circulating lipoprotein(a) [Lp(a)]. The apo(a) gene is highly homologous to the plasminogen gene. It encodes one of the most polymorphic human proteins, due to variability in the number of repetitions of structures called kringles. I...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Malgaretti, N, Acquati, F, Magnaghi, P, Bruno, L, Pontoglio, M, Rocchi, M, Saccone, S, Della Valle, G, D'Urso, M, LePaslier, D
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11584
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