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Characterization by yeast artificial chromosome cloning of the linked apolipoprotein(a) and plasminogen genes and identification of the apolipoprotein(a) 5' flanking region.

The apoprotein(a) [apo(a)] gene encodes a protein component of the circulating lipoprotein(a) [Lp(a)]. The apo(a) gene is highly homologous to the plasminogen gene. It encodes one of the most polymorphic human proteins, due to variability in the number of repetitions of structures called kringles. I...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Malgaretti, N, Acquati, F, Magnaghi, P, Bruno, L, Pontoglio, M, Rocchi, M, Saccone, S, Della Valle, G, D'Urso, M, LePaslier, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1992
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50597/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11584
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